America's top dog is back, and this time, he's bringing the kids! Charles Grodin and Bonnie Hunt star in this hilarious comedy about the further adventures of the Newton family and their lovable, lumbering pal, Beethoven. In the second "symphony" of the "Beethoven" saga, our hero meets Missy, the lady Saint Bernard of his dreams. Unfortunately, they are soon separated by Regina, Missy's hateful owner who is using her as a bargaining chip in an ugly divorce. Will Missy, Beethoven and their puppies ever be reunited? And will Regina finally get what she deserves?